1.
Asian Pac J Allergy Immunol
;
1986 Dec; 4(2): 101-5
Article
in English
| IMSEAR
| ID: sea-36879
ABSTRACT
The determination of acetylcholine receptor antibody (AChR Ab) titer by an enzyme-linked immunosorbent assay (ELISA) in patients with myasthenia gravis was introduced. The optimal conditions were determined by chequerboard determination. The specificity was confirmed by inhibition tests. The sensitivity is 9 p mole. The comparison of AChR Ab titers among 49 myasthenic patients, 19 non-myasthenic neurological patients and 20 healthy blood donors has shown that it is a highly sensitive, specific, reproducible, rapid, simple and inexpensive method for determining AChR Ab and that it is highly valuable for the diagnosis of myasthenia gravis.
Subject(s)
Antigen-Antibody Complex , Autoantibodies/analysis , Enzyme-Linked Immunosorbent Assay , Humans , Kinetics , Myasthenia Gravis/immunology , Receptors, Cholinergic/immunology
2.
Asian Pac J Allergy Immunol
;
1985 Jun; 3(1): 9-15
Article
in English
| IMSEAR
| ID: sea-37239